The research objective is to study the wisdoms influencing the community economy development of the communities in Phayao. The quantitative methodology was conducted. The data was collected by interviewing with the 232 household head. Data analysis is multiple regression. The results were found that: Demotions of wisdom, livelihood, social relation, and religion and believe are positive influence on the community economy development with statistical significance at .05. When considering the wisdom that has the best power to predict the changes of community economic development, it is found that social relations has the most power to predict changes in community economic development. Which has a standard regression coefficient (β) equal to. 413. The following is livelihood which has a standard regression coefficient (β) equal to .277, religion and belief which has a standard regression coefficient (β) equal to. 184 and a handicraft which has a standard regression coefficient (β) equals.177respectively. It can explain the variability of community economic development 51.9 percent (R2 Adjust = .519). And there is a standard deviation in the model estimation of 11.34999 (Std.EE. = 11.34999).